Ciba Foundation Symposium - Control Processes in by Gordon E. W. Wolstenholme, Julie Knight

By Gordon E. W. Wolstenholme, Julie Knight

Chapter 1 Chairman's commencing comments (pages 1–2): F. G. Young
Chapter 2 In vitro stories of the Lac Operon Regulatory approach (pages 3–20): Suzanne Bourgeois and Jacques Monod
Chapter three Modulation of Enzyme actions by way of Metabolites (pages 28–51): F. Lynen
Chapter four The Expression of Genetic details: A research with Hybrid Animal Cells (pages 52–63): Henry Harris
Chapter five The position of Cyclic AMP in yes organic regulate structures (pages 64–85): R. W. Butcher, G. A. Robison and E. W. Sutherland
Chapter 6 Insulin and development Hormone keep watch over of Protein Biosynthesis (pages 86–107): A. Korner
Chapter 7 Mechanism of motion of progress Hormone and Oestrogens (pages 108–130): G. P. Talwar, B. L. Jailkhani, S. ok. Sharma, M. L. Sopori, M. R. Pandian, G. Sundharadas and ok. N. Rao
Chapter eight Hormonal keep an eye on of Metamorphosis (pages 131–157): J. R. Tata
Chapter nine Intercellular keep watch over of Intracellular Metabolic job (pages 158–177): P. M. Bhargava
Chapter 10 contemporary reports at the suggestions keep watch over of Acth Secretion, with specific connection with the position of Transcortin in Pituitary?Thyroid?Adrenocortical Interactions (pages 178–209): Claude Fortier, Fernand Labrie, Georges Pelletier, Jean?Pierre Raynaud, Pierre Ducommun, Alfonso Delgado, Robert Labrie and My?Anh Ho?Kim
Chapter eleven The function of the Thymus Gland within the Hormonal legislation of host Resistance (pages 210–237): Abraham White and Allan L. Goldstein
Chapter 12 interplay among Thymus Cells and Bone Marrow Cells according to Antigenic Stimulation (pages 237–254): J. F. A. P. Miller and G. F. Mitchell
Chapter thirteen Anticipatory Mechanisms of Indivduals (pages 254–303): Melvin Cohn
Chapter 14 Antibody constitution: A Molecular foundation for Specificity and keep watch over within the Immune reaction (pages 304–320): Gerald M. Edelman
Chapter sixteen Regulatory Mechanisms of mobile Proliferation in a Protein?Deficient Organism (pages 321–337): M. G. Deo and V. Ramalingaswami
Chapter sixteen Subcellular Fractionation suggestions within the examine of Chemical. Transmission within the principal apprehensive approach (pages 338–356): V. P. Whittaker
Chapter 17 rules of Visceral Actmtes through the significant anxious approach (pages 355–384): B. okay. Anand
Chapter 18 a few common Integrative features of mind functionality (pages 384–415): Robert B. Livingston
Chapter 19 Chairman's ultimate feedback (page 416): F. G. younger

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Extra resources for Ciba Foundation Symposium - Control Processes in Multicellular Organisms

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As can also be seen in the table, the level decreases when sugar is fed, a condition which leads to increased fatty acid synthesis. As Bshmer, Norum and Bremer (1966) have shown, the level of long-chain acyl-carnitines in liver corresponds to the level of long-chain acyl CoA derivatives in the different nutritional or hormonal states of the animal. 3 Wieland et al. (1965) acetyl CoA carboxylase. Therefore it is tempting to speculate that fatty acid synthesis, at least in liver, is under negative feedback control.

Mol. weight: 4 400 OW mol. 3. Hypothetical structures of the various forms of acetyl CoA carboxylasc (Henniger, I969). is indicated by the fact that there is a single biotinyl prosthetic group on the 410o o o - ~ o 000 molecular weight protomer. By treating the enzyme with 6hi-guanidine* HC1 in phosphate buffer and in the presence of meraptoethanol Henniger (1969) detected even subunits possessing a molecular weight of about 60000. The results of these dissociation METABOLITE M O D U L A T I O N OF ENZYMES 37 experiments seem to indicate that the “smau” form of acetyl CoA carboxylase itself must have a rather complex quaternary structure.

Biochem. biophys. Res. E. (I*). , 28,682. P. CHANGBUX, J. P. (161). Cold Spring Hmb. S p p . pant. BioL, 26, 313. Corn,C. , and Corn,G. T. , 158, 341. , rag, 803. ,and LOWENSTEIN, 46 P. physiol. , 26, 60. FRITZ,I. B. (1961). Physiof. , 41,52. GANGULY, J. (1960). Biodlini. biophys. Ada, 40, I 10. , and BENJAMIN, W. (I*). Adv. E n z p Regulation, 4,19. GERHAIU). J. ,and P m m , A. B. Fedn Roc. Fedn Am. Socs exp. , 20, 224. GERHARD, J. , and PABDEE,A. B. J. bid. , 237, 891. GIBSON, D. , H m s , S.

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