Athlete Performance and Injuries by Joao H. Bastos

By Joao H. Bastos

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Considering the entire context presented above, the importance of research on natural antioxidants has increased greatly in recent years. Since the 1980s there has been a considerable broadening of the search for natural antioxidants that can be included in the diet as substitutes for synthetic antioxidants (Degáspari and Waszczynskyj, 2004). , 2011a). , 2011b). Although the protective effects of pequi oil are unquestionable, some of these responses were influenced by genetic polymorphisms related to oxidative stress and inflammatory markers.

2004), besides the heterozygous AT being associated with higher values of mean corpuscular hemoglobin (MCH) in runners. , 2010a). , 2011b). 3. Glutathione Peroxidase (GPX) The glutathione peroxidase family is the largest of the selenoprotein gene families. 9) are named for their ability to use glutathione as a reducing substrate. , 2006). GPX3 (extracellular or plasma) is a circulating plasma selenoprotein and is able to utilize thioredoxin reductase, thioredoxin or glutaredoxin as reductants.

2008), besides exerting an impact on femoral mechanical characteristics, impairing femoral bending strength and stiffness in growing knockout female mice. , 2003). Mitochondria are the major source of reactive oxygen species in a resting cell. If antioxidant protection is inadequate this will result in oxidative stress and cause mitochondrial dysfunction. , 2007). , 2007). The common polymorphism consisting of a single 20 Ana Luisa Miranda-Vilela nucleotide change in the region of the DNA encodes the signal sequence, such that the presence of either an alanine or a valine has been suggested; these would induce a conformational change from an α-helix to a β-sheet.

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